Severe Acute Respiratory Syndrome-Coronavirus Disease (COVID-19): A Review

Mohd Wamique1, Bilal Ahmad2, Anchal Trivedi3, D.Himashu1, Hifzur Rahman4, Jalal Ahmad5 , Tahsin Raza6, Saliha Rizvi7*

1Department of Infectious diseases, King George’s Medical University, 2Era’s Lucknow Medical College, 3Department of Biochemistry, Era’s Lucknow Medical College, 4Research Associate (Unani) in National Programme For Prevention and Control of Cancer, Diabetes, Cardiovascular Disease and Stroke at Community Health Center, Lakhimpur, 5Department of Microbiology, Era’s Lucknow Medical College, 6Department of Physiology, Era’s Lucknow Medical College, 7Department of Biotechnology, Era’s Lucknow Medical College, Lucknow, Uttar Pradesh 226003, India

*Corresponding Author: Dr. Saliha Rizvi, Assistant Professor, Department of Biotechnology, Era’s Lucknow Medical College, Lucknow, Uttar Pradesh 226003, India. E-mail: [email protected]

Severe Acute Respiratory Syndrome (SARS-CoV-2) is the most dangerous pandemic of the 21st century and the main epicenter of Coronavirus disease (COVID-19) is Wuhan in the Hubei province of China. Coronavirus is so-called because of the spike on its surface (corona= crown) that belongs to coronvirinaesubfamily. There are mainly four groups like alpha, beta, gamma, delta established on their genomic assembly. The review focuses on brief introduction to coronaviruses discussing the role of rennin-angiotensin system in hypertensive and coronary vascular disease. Based on the published evidence, we also discuss genetic risk of COVID-19. This review article also highlights current developments in designing vaccines and therapeutics in the hope of providing a reference for future studies and help for the prevention of the COVID-19 epidemic.

Keywords: COVID-19, Pandemic, SARS-CoV-2

Citation: Mohd Wamique, Bilal Ahmad, Anchal Trivedi, D. Himashu, Hifzur Rahman, Jalal Ahmad, Tahsin Raza, Saliha Rizvi. Severe Acute Respiratory Syndrome-Coronavirus Disease (COVID-19): A Review. Canadian Journal of Clinical Nutrition. 2021; 9 (2): 64-74.