Zahir Al-Attabi, Rima AlMamri, Khadija Al Abd Aslam
Department of Food Science and Nutrition, College of Agricultural and Marine Sciences, Sultan Qaboos University, Muscat, Oman
*Corresponding Author: Dr. Zahir Al-Attabi. Email: firstname.lastname@example.org
Background: Glutathione (GSH) protects against oxidative stress by combating reactive oxygen species (ROS) generation produced by hydrogen peroxide (H2O2) as an in-vitro oxidizing agent. Objective: This study aimed to investigate the in-vitro protective effects of three wild Omani plants against H2O2- induced oxidative stress in rat liver. Methods: Three Omani wild plants, Portulaca Olereaca L (Farfenaa) , Pteropyrum Scoparium (Sidaf) and Caralluma Arabica (Addaja) have been investigated for their antioxidant activity. The extracts were prepared by freeze drying and subjected to Glutathione (GSH) and total antioxidant capacity (TAC) assays in the presences of 0.1 % H2O2. Results: The results revealed that 0.1% H2O2 treatment induces in-vitro oxidative stress as evidenced by GSH depletion and decrease TAC levels. Pre-treatment with the plants extracts augmented the 0.1% H2O2 -induced Glutathione depletion and improved the TAC level. The potency of the free radical scavenging property was the highest in Farfenaa, followed by Addaja and Sidaf. Conclusion: The results obtained suggest that consumption of the three Omani wild plants, as an antioxidant-rich food, might reduce cellular oxidative stress and its related health problems.
Keywords: Wild Omani Plants, Oxidative Stress, Dietary Antioxidants
Al-Attabi Z, AlMamri R, Al AbdAslam K. Antioxidant potential properties of three Wild Omani plants against hydrogen peroxide-induced oxidative stress. Canad J Clin Nutr 2015; 3 (2): 16-22Download