The Relationship between Serum 25-hydroxyvitamin D Concentration and Handgrip Strength in Adult Men: A Cross-sectional Study

Chi. Q. T. Vu1,2*, Khuyen. T. Tran2
1Nutritional Epidemiology Institute and School of Public Health, Tianjin Medical University, China, 2Public Health Faculty, Thai Binh University of Medicine and Pharmacy, Viet Nam
*Corresponding Author Email Address: quynhchiytb@gmail.com

ABSTRACT
Background: Decline in handgrip strength (HGS) in the aging process is associated with several adverse outcomes, including future disability, hospitalization, and mortality. Many of the previous studies demonstrated a significant relationship between vitamin D and HGS, but these studies performed in participants with a broad age range and got conflicting results.
Objective: This study aimed to investigate the association between serum 25(OH)D concentration and Handgrip strength in Chinese adult men stratified by 50 years old. Participants and Methods: This is a cross-sectional with 2,688 participants in Tianjin, China. Handgrip strength was measured using an electronic handgrip dynamometer (EH101. CAMRY, Guangdong, China). The serum 25(OH)D concentration was measured an enzyme immunoassay. Analysis of covariance (ANCOVA) was used assessing the association between serum 25(OH)D concentration and grip strength with adjustment for the confounder variables. Results: A total of 2,688 subjects participated in this study. For participants who have age above 50 years, after adjustment for confounded variable, the mean (95%CI) of handgrip strength (HGS) per body weight (kg/kg) across serum 25(OH)D concentration quartiles were 0.52, (0.42, 0.64); 0.54, (0.44, 0.67); 0.54, (0.44, 0.67), and 0.54, (0.44, 0.67); (Ptrend<0.01), and the mean (95%CI) of HGS were 37.0, (29.7, 46.1); 38.7, (31.1, 48.2); 38.6, (31.0, 48.0), and 38.8, (31.2, 48.2); (Ptrend<0.01). There were no significant differences in serum 25(OH)D concentration quartiles both HGS per body weight and HGS with participants below 50 years old. Conclusion: Serum 25(OH)D concentration was significantly related to HGS in men who have age above 50 years. This study suggested that improving HGS by vitamin D supplement to reduce the risk of health including sarcopenia.

Keywords: Serum 25-hydroxyvitamin D, Handgrip Strength, vitamin D Citation: Chi. Q. T. Vu, Khuyen. T. Tran. The Relationship between Serum 25- hydroxyvitamin D Concentration and Handgrip Strength in Adult Men: A Cross-sectional Study. Canad J Clin Nutr. 2019; 7 (1): 34-45.
DOI: http://dx.doi.org/10.14206/canad.j.clin.nutr.2019.01.04

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