The Acrylamide Dietary Intake Effect during Pregnancy on the Cord Blood Level of 2,3-Dibromopropionamide and Birth Outcomes of the Newborns: A Pilot Study

Walaa M.R. El-Meidany*, Dalia I. Tayel
Department of Nutrition, High Institute of Public Health, Alexandria University, Alexandria, Egypt
*Corresponding Author Email Address: w.elmaidany@alexu.edu.eg

ABSTRACT
Background: The Joint FAO/WHO Expert committee on food additives reviewed the available data on the safety of acrylamide (AA) and concluded that its presence in food represents a health concern. Fetal exposure to AA through the diet may start in utero as acrylamide can cross the placental barrier and so there has been a concern about the health risk to the unborn child. Objective: A pilot study was done on 20 pregnant women to assess the dietary intake of AA consumed during their pregnancy, to determine the birth weight and head circumferences of these women’s newborns, and to detect the level of acrylamide metabolite (2,3- dibromopropionamide) in the cord blood immediately after delivery using the Gas Chromatography. Participants and Methods: A hospital based cross-sectional study included 20 pregnant women attending Alexandria University Obstetrics and Gynecology Hospital. Results: The obtained results showed a negative relationship between the cord blood level of AA in both birth weight and head circumference of the newborns. Conclusion: There was a statistically significant difference between the cord blood level of AA and the birth weight of the newborns. Further researches are needed to assess the long-term health effects of AA on the newborns exposed during pregnancy.

Keywords: Acrylamide Dietary Intake, Birth Weight, Cord Blood, Newborns
Citation: El-Meidany WMR, Tayel DI. The Acrylamide Dietary Intake Effect during Pregnancy on the Cord Blood Level of 2,3-Dibromopropionamide and Birth Outcomes of the Newborns: A Pilot Study. Canad J Clin Nutr 2019; 7 (1): 78-88.
DOI: http://dx.doi.org/10.14206/canad.j.clin.nutr.2019.01.07

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