Abnormalities of Amyloid Precursor Protein in the Etiology of Alzheimer’s disease

Mostafa I. Waly

Department of Food Science and Nutrition, College of Agricultural and Marine Sciences, Sultan Qaboos University, Muscat, Oman

Corresponding Author: waly.mostafa@gmail.com

ABSTRACT
Alzheimer’s disease (AD) is a widespread neurodegenerative disorder of the elderly population. AD was first characterized by Alois Alzheimer in 1907, who reported the remarkable observation that persons diagnosed with AD are suffering from lossof their identity,memories, cognitive, and physical functioning. In 1900, the global average life expectancy was 47 years, so few people lived long enough to experience the onset of AD, but now the life expectancy is 75 years. Currently, 4 million people are affected with AD and 250,000 more cases are diagnosed annually worldwide. This steady increase in AD cases is associated with an increase in the medical care and long term rehabilitation services. Amyloid precursor proteinis thought to be responsible for the pathology and subsequent cognitive and mental decline in patients with AD.

Keywords: Alzheimer’s disease, Elderly Population, Amyloid Precursor Protein

Waly MI. Abnormalities of Amyloid Precursor Protein in the Etiology of Alzheimer’s Disease. Canad J ClinNutr 2015; 3 (1): 1-3

DOI:http://dx.doi.org/10.14206/canad.j.clin.nutr.2015.01.01

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